Allgemein

Annabelle successfully defended her PhD thesis "Tools for the Characterization of New Modality Drugs Targeting RNA Methyltransferases and Lectins" - congratulations Dr. Weldert!

 

We currently have one PhD position available with a focus on chemical biology, specifically RNA-ligand interactions and antibacterial drug discovery.

 

The application period has closed. Please do not submit any further applications for this position.

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Ariane successfully defended her PhD thesis "Nanoscale Libraries and Novel Drug Modalities for Targeting RNA Methyltransferases" - congratulations Dr. Hübner!

Congratulations! Valerie Kadenbach wins the Best Poster Award at the Frontiers in Medicinal Chemistry (FiMC) annual meeting 2026 in Münster.

In a great collaboration with the Ziebuhr Lab and the Wolf Lab, we have developed a Direct-to-Biology (D2B) pipeline for the discovery of potent S. aureus TrmD inhibitors.
Check out the recent publication in Journal of Medicinal Chemistry: Nanoscale Direct-to-Biology Optimization and Structural Insights into Selective S. aureus TrmD Inhibitors

We are thrilled to announce a publication hat-trick from the group! Three of our latest studies have just been published in iScience, RSC MedChem, and Communications Chemistry. We warmly thank all team members and collaboration partners whose dedication made this achievements possible.

Check out our most recent publication in Angewandte Chemie:
Nanomole Scale Screening of Fluorescent RNA-Methyltransferase Probes Enables the Discovery of METTL1 Inhibitors

In the course of this invention, we are happy to share our developed MTase probes with fellow RNA researchers:
Request probes here

Ariane and Annabelle represented our research group at the DPhG annual PhD/PostDoc meeting in Marburg, presenting our latest research findings. To complete the trip, they both won the awards for the best presentation and the mentoring prize. Kudos to their dedication and expertise!

Congratulations! Ariane Frey wins the Best Poster Award at the DPhG annual meeting 2023 in Tübingen.

Check out our latest paper in RSC Chemical Science. Using non-covalent nucleic acid dyes, we developed an RNA-MST-based protocol for the study of RNA ligands and modifications.

https://pubs.rsc.org/en/content/articlelanding/2023/SC/D3SC02993J