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Johannes Gutenberg University Mainz
Barthels LabInstitute of Pharmaceutical and Biomedical Sciences
Johannes Gutenberg University Mainz
Barthels LabInstitute of Pharmaceutical and Biomedical Sciences
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    • Dr. Fabian Barthels
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D2B enables the discovery of potent S. aureus TrmD inhibitors

In a great collaboration with the Ziebuhr Lab and the Wolf Lab, we have developed a Direct-to-Biology (D2B) pipeline for the discovery of potent S. aureus TrmD inhibitors.
Check out the recent publication in Journal of Medicinal Chemistry: Nanoscale Direct-to-Biology Optimization and Structural Insights into Selective S. aureus TrmD Inhibitors

Posted on 10. January 2026 | Posted in Allgemein
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Blog archive

  • Valerie presents our research at the FiMC in Münster 27. March 2026
  • D2B enables the discovery of potent S. aureus TrmD inhibitors 10. January 2026
  • Publication hat-trick 2025 6. August 2025
  • Our MTase probes in Angewandte Chemie 15. August 2024
  • Ariane and Annabelle present our research in Marburg 24. March 2024
  • Ariane wins Poster Award at DPhG 11. October 2023
  • Non-covalent dyes for RNA-MST 5. September 2023
Dr. Fabian Barthels
Akademischer Rat
Johannes Gutenberg-Universität Mainz
Institute of Pharmaceutical and Biomedical Sciences
Staudingerweg 5
55128 Mainz, Germany

Telefon: +49 6131 39-30544
E-Mail: barthels@uni-mainz.de

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  • Page-Name:Institute of Pharmaceutical and Biomedical Sciences
  • Last Update:27. March 2026
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